ATG7 Monoclonal Antibody

Uniprot : O95352
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
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    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience

      Catalog number:E-AB-22151

      Synonyms:1810013K23Rik,Apg 7,APG7 autophagy 7 like,APG7 autophagy 7-like (S. cerevisiae),APG7 like,APG7,S. cerevisiae,homolog of,APG7-like,APG7L,ATG 7,ATG12-activating enzyme E1 ATG7,ATG7,ATG7 autophagy related 7 homolog (S. cerevisiae),ATG7 autophagy related 7 homolog,ATG7,Atg7l,Autophagy 7,S. cerevisiae,homolog of,Autophagy related protein 7,Autophagy-related 7 (yeast),Autophagy-related protein 7,DKFZp434N0735,GSA 7,GSA7,hAGP7,Ubiquitin activating enzyme E1 like protein,Ubiquitin-activating enzyme E1-like protein,Ubiquitin-like modifier-activating enzyme ATG7

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Mouse

      Reactivity: H,M,R

      Applications: IHC-p,IF

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms 1810013K23Rik,Apg 7,APG7 autophagy 7 like,APG7 autophagy 7-like (S. cerevisiae),APG7 like,APG7,S. cerevisiae,homolog of,APG7-like,APG7L,ATG 7,ATG12-activating enzyme E1 ATG7,ATG7,ATG7 autophagy related 7 homolog (S. cerevisiae),ATG7 autophagy related 7 homolog,ATG7,Atg7l,Autophagy 7,S. cerevisiae,homolog of,Autophagy related protein 7,Autophagy-related 7 (yeast),Autophagy-related protein 7,DKFZp434N0735,GSA 7,GSA7,hAGP7,Ubiquitin activating enzyme E1 like protein,Ubiquitin-activating enzyme E1-like protein,Ubiquitin-like modifier-activating enzyme ATG7
      Swissprot O95352
      Source Mouse
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant Protein of ATG7
      Application IHC-p(Detection kit: E-IR-R217),IF
      Recommended dilution IHC 1:50-300, IF 1:50-1:200
      Concentration 1 mg/mL
      Clonality Monoclonal

      Properties

      Cellular localization Cytoplasm. Preautophagosomal structure. Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme.
      Tissue specificity Widely expressed, especially in kidney, liver, lymph nodes and bone marrow.
      Clone No. Clone:1A1
      Isotype IgG
      Purification Protein A purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
      Background ATG7 (Autophagy Related 7) is a Protein Coding gene. Among its related pathways are Autophagy Pathway and Innate Immune System. GO annotations related to this gene include protein homodimerization activity and ubiquitin activating enzyme activity. This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.

      Images

      monoclonal antibody-Elabscience

      Immunohistochemistry of paraffin-embedded Human uterus tissue using ATG7 Monoclonal Antibody at dilution of 1:200.

      monoclonal antibody-Elabscience

      Immunofluorescence analysis of Mouse spleen tissue using ATG7 Monoclonal Antibody at dilution of 1:200.

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