AUP1 Polyclonal Antibody

Uniprot : Q9Y679
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14564

      Synonyms:AA589454,Ancient ubiquitous protein 1,AUP 1,aup1,AUP1

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms AA589454,Ancient ubiquitous protein 1,AUP 1,aup1,AUP1
      Swissprot Q9Y679
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human AUP1
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:50-1:200
      Concentration 0.5 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Endoplasmic reticulum membrane.
      Tissue specificity Detected in blood platelets and leukocytes (at protein level). Ubiquitous. Highly expressed in placenta, liver, kidney, skeletal muscle, heart and brain.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25.

      Images

      Western Blot analysis of Hela and 293T cell, Mouse liver tissue and NIH/3T3 cell using AUP1 Polyclonal Antibody at dilution of 1:500

      Immunohistochemistry of paraffin-embedded Human liver cancer using AUP1 Polyclonal Antibody at dilution of 1:50

      Immunohistochemistry of paraffin-embedded Human lung cancer using AUP1 Polyclonal Antibody at dilution of 1:50

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