Biotin Anti-Human CD274/PD-L1 Antibody[29E.2A3]

All	Size	Price	Qty
	100μg	$ 144.00
	25μg	$ 58.00

Alternate Names	B7H1PD-L1PDCD1L1PDCD1LG1PDL1, B7 homolog 1, B7-H, B7-H1, Programmed cell death ligand 1
Clone No	29E.2A3
Leadtime	Order now, ship in 3 days
Background	CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
Abbre	PD-L1
Swissprot	Q9NZQ7
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Isotype	Mouse IgG2b, κ
Isotype Control	E-AB-F09813B
Applications	FCM
Research Areas	Cancer Biomarkers;Costimulatory Molecules;Immunology
Cellular Localization	Membrane
Form	Liquid
Concentration	0.5 mg/mL
Conjugation	Biotin
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage	This product can be stored at 2-8°C for 12 months. Do not freeze.
Expiration Date	12 months
Shipping	Ice bag

Cat.No.	Product Name	Sizes
E-CK-A105	10×ACK Lysis Buffer	500mL , 200mL , 100mL
E-CK-A107	Cell Staining Buffer	500mL , 200mL , 100mL

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29E.2A3

Biotin Anti-Human CD274/PD-L1 Antibody[29E.2A3] (E-AB-F1133B)