Current Position:Home>>Antibodies>>Flow Cytometry Antibodies>> Biotin Anti-Mouse CD132 Antibody[3E12] E-AB-F1015B
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|Alternate Names||Cytokine receptor common subunit gamma,Il2rg,Interleukin-2 receptor subunit gamma,IL-2 receptor subunit gamma,IL-2R subunit gamma,IL-2RG,gammaC,p64,CD132|
1. Itano M, et al. 1996. Tohoku J. Exp. Med. 178:389.
2. Zola H, et al. eds. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. Wiely-Liss A John Wiley & Sons Inc, Publication .
3. Nakarai T, et al. 1994. J. Exp. Med. 180:241.
4. Kawahara A, et al. 1995. Proc. Natl. Acad. Sci. USA. 92:8724.
5. Habib T, et al. 2002. Biochemistry. 41:8725.
6. Matthews DJ, et al. 1995. Blood 85:38.
|Clone No.||3E12(See Other Available Formats)|
|Isotype||Rat IgG2b, κ|
|Isotype Control||Biotin Rat IgG2b, κ Isotype Control[LTF-2] [Product E-AB-F09843B]|
|Application||FCM (See the Application Description)|
|Storage Buffer||Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.|
|Recommended Use||Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.|
|Shipping||Biological ice pack at 4℃|
|Stability & Storage||Keep as concentrated solution.
Store at 2~8°C. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
How to select the appropriate detection channel through the spectrogram?
|CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).|
|Related Protocols||Staining Cell Surface Targets for Flow Cytometry|
|AF/LE Purified Anti-Mouse CD132 Antibody[3E12] E-AB-F10150||50μg, 500μg, 1mg||Check More|
|Purified Anti-Mouse CD132 Antibody[3E12] E-AB-F1015A||25μg, 100μg||Check More|
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