Current Position:Home>>Antibodies>>Flow Cytometry Antibodies>> Biotin Anti-Mouse CD132 Antibody[3E12] E-AB-F1015B
Cat.No.:E-AB-F1015B
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Alternate Names | Cytokine receptor common subunit gamma,Il2rg,Interleukin-2 receptor subunit gamma,IL-2 receptor subunit gamma,IL-2R subunit gamma,IL-2RG,gammaC,p64,CD132 |
Swissprot | P34902 |
References |
1. Itano M, et al. 1996. Tohoku J. Exp. Med. 178:389.
2. Zola H, et al. eds. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. Wiely-Liss A John Wiley & Sons Inc, Publication . 3. Nakarai T, et al. 1994. J. Exp. Med. 180:241. 4. Kawahara A, et al. 1995. Proc. Natl. Acad. Sci. USA. 92:8724. 5. Habib T, et al. 2002. Biochemistry. 41:8725. 6. Matthews DJ, et al. 1995. Blood 85:38. |
Form | Liquid |
Clone No. | 3E12(See Other Available Formats) |
Host | Rat |
Isotype | Rat IgG2b, κ |
Isotype Control | Biotin Rat IgG2b, κ Isotype Control[LTF-2] [Product E-AB-F09843B] |
Reactivity | Mouse |
Application | FCM (See the Application Description) |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Recommended Use | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Shipping | Biological ice pack at 4℃ |
Stability & Storage | Keep as concentrated solution. Store at 2~8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Conjugation | Biotin |
How to select the appropriate detection channel through the spectrogram?
CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID). |
Related Protocols | Staining Cell Surface Targets for Flow Cytometry |
Troubleshooting |
Product Name | Sizes | Price |
AF/LE Purified Anti-Mouse CD132 Antibody[3E12] E-AB-F10150 | 50μg, 500μg, 1mg | Check More |
Purified Anti-Mouse CD132 Antibody[3E12] E-AB-F1015A | 25μg, 100μg | Check More |
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