Alternate Names	Cytokine receptor common subunit gamma,Il2rg,Interleukin-2 receptor subunit gamma,IL-2 receptor subunit gamma,IL-2R subunit gamma,IL-2RG,gammaC,p64,CD132
Swissprot	P34902
References	1. Itano M, et al. 1996. Tohoku J. Exp. Med. 178:389. 2. Zola H, et al. eds. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. Wiely-Liss A John Wiley & Sons Inc, Publication . 3. Nakarai T, et al. 1994. J. Exp. Med. 180:241. 4. Kawahara A, et al. 1995. Proc. Natl. Acad. Sci. USA. 92:8724. 5. Habib T, et al. 2002. Biochemistry. 41:8725. 6. Matthews DJ, et al. 1995. Blood 85:38.

Product Details

Form	Liquid
Clone No.	3E12(See Other Available Formats)
Host	Rat
Isotype	Rat IgG2b, κ
Isotype Control	Biotin Rat IgG2b, κ Isotype Control[LTF-2] [Product E-AB-F09843B]
Reactivity	Mouse
Application	FCM (See the Application Description)
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Recommended Use	Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10⁶ cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	Biotin

How to select the appropriate detection channel through the spectrogram?

Background

CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).

Protocols & Troubleshootings

Related Protocols	Staining Cell Surface Targets for Flow Cytometry
Troubleshooting	Troubleshooting for Flow Cytometry

Alternative Formats

Product Name	Sizes	Price
AF/LE Purified Anti-Mouse CD132 Antibody[3E12]	50μg, 500μg, 1mg	Check More
Purified Anti-Mouse CD132 Antibody[3E12]	25μg, 100μg	Check More

Citations

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