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For research use only.

Verified Samples Verified Samples in IHC: Human tonsil, Human gastric cancer, Rat ovary, Mouse liver
Verified Samples in IF: L929
Dilution IHC 1:50-1:200,  IF 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC,  IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human BMPR1B (NP_001194.1).
Abbre BMPR1B
Synonyms ALK-6,  ALK6,  AMDD,  BDA1D,  BDA2,  BMPR1B,  CDw293
Swissprot
Cellular Localization Membrane.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling,  Signal Transduction,  Stem Cells
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene.
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Unconjugated

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