BPI Polyclonal Antibody

Uniprot : P17213
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14800

      Synonyms:Bactericidal permeability-increasing protein,Bactericidal/permeability increasing protein,BPI,BPI fold containing family D,member 1,BPI,BPIFD1,CAP 57,CAP57,rBPI,Recombinant BPI holoprotein,rBPI

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Bactericidal permeability-increasing protein,Bactericidal/permeability increasing protein,BPI,BPI fold containing family D,member 1,BPI,BPIFD1,CAP 57,CAP57,rBPI,Recombinant BPI holoprotein,rBPI
      Swissprot P17213
      Source Rabbit
      Reactivity Human
      Immunogen Recombinant protein of human BPI
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.6 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Secreted. Cytoplasmic granule membrane. Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.
      Tissue specificity Restricted to cells of the myeloid series.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background This gene encodes a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has bactericidal activity on gram-negative organisms. The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.

      Images

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using BPI Polyclonal Antibody at dilution 1:50

      Immunohistochemistry of paraffin-embedded Human liver cancer tissue using BPI Polyclonal Antibody at dilution 1:50

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