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For research use only.

Verified Samples Verified Samples in IHC: Human lung cancer, Human stomach cancer, Mouse liver, Rat brain, Human liver
Dilution IHC 1:200-1:1000
Isotype Rabbit IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen KLH conjugated Synthetic peptide corresponding to Mouse c-FOS
Abbre c-Fos
Synonyms Activator protein 1,  AP 1,  C FOS,  Cellular oncogene c fos,  Cellular oncogene fos,  FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS),  FBJ murine osteosarcoma viral oncogene homolog,  FBJ murine osteosarcoma viral v fos oncogene homolog,  FBJ Oste
Swissprot
Cellular Localization Cytoplasm, Endoplasmic reticulum, Nucleus.
Concentration 0.55 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling,  Neuroscience
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
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