CALCOCO1 Polyclonal Antibody (E-AB-52770)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human cervical cancer, Human esophagus cancer |
| Dilution | IHC 1:30-1:150 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human CALCOCO1 |
| Abbre | CALCOCO1 |
| Synonyms | Calcium binding and coiled coil domain 1, CALCOCO1, Calphoglin, Coiled coil coactivator protein, Coiled coil leucine zipper coactivator 1, Coiled coil transcriptional coactivator, Inorganic pyrophosphatase activator, KIAA1536, PP13275, Sarcoma antigen NY-SAR |
| Swissprot | |
| Cellular Localization | Cytoplasm. Nucleus. Note: shuttles between nucleus and cytoplasm. |
| Concentration | 0.72 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | CALCOCO1 (calcium-binding and coiled-coil domain-containing protein 1), also known as cocoa, calphoglin, sarcoma antigen NY-SAR-3 or coiled-coil coactivator protein, is a 691 amino acid protein that shuttles between the cytoplasm and nucleus and functions as coactivator for aryl hydrocarbon and nuclear receptors. A member of the CALCOCO family, CALCOCO1 is forms a calphoglin complex with PPA1 and PGM 1 and contains multiple functional domains through which it acts as a component of both the androgen signaling pathway and the Wnt/β-catenin signaling pathway. CALCOCO1 exists as three alternatively spliced isoforms (termed Q9P1Z2-1, 2 and 3), which are encoded by genes mapping to human chromosome 12q13.13 and mouse chromosome 15 F3. |
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