CALCOCO1 Polyclonal Antibody (E-AB-52770)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human cervical cancer, Human esophagus cancer |
| Dilution | IHC 1:30-1:150 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human CALCOCO1 |
| Abbre | CALCOCO1 |
| Synonyms | CALCOCO1, Calcium binding and coiled coil domain 1, Calphoglin , Coiled coil coactivator protein, Coiled coil leucine zipper coactivator 1 , Coiled coil transcriptional coactivator , Inorganic pyrophosphatase activator , KIAA1536 , PP13275 , Sarcoma antigen NY-SAR |
| Swissprot | |
| Cellular Localization | Cytoplasm. Nucleus. Note: shuttles between nucleus and cytoplasm. |
| Concentration | 0.72 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | CALCOCO1 (calcium-binding and coiled-coil domain-containing protein 1), also known as cocoa, calphoglin, sarcoma antigen NY-SAR-3 or coiled-coil coactivator protein, is a 691 amino acid protein that shuttles between the cytoplasm and nucleus and functions as coactivator for aryl hydrocarbon and nuclear receptors. A member of the CALCOCO family, CALCOCO1 is forms a calphoglin complex with PPA1 and PGM 1 and contains multiple functional domains through which it acts as a component of both the androgen signaling pathway and the Wnt/β-catenin signaling pathway. CALCOCO1 exists as three alternatively spliced isoforms (termed Q9P1Z2-1, 2 and 3), which are encoded by genes mapping to human chromosome 12q13.13 and mouse chromosome 15 F3. |
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