Synonyms:Calnexin,CALX,CANX,CNX,FLJ26570,Histocompatibility complex class I antigen binding protein p88,IP90,Major histocompatibility complex class I antigen-binding protein p88,p90
|Synonyms||Calnexin,CALX,CANX,CNX,FLJ26570,Histocompatibility complex class I antigen binding protein p88,IP90,Major histocompatibility complex class I antigen-binding protein p88,p90|
|Immunogen||Synthesized peptide derived from human Calnexin around the non-phosphorylation site of Ser583.|
|Application||WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213),IF,ELISA|
|Recommended dilution||WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000|
|Cellular localization||Endoplasmic reticulum membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.|
|Storage instructions||Store at -20℃. Avoid freeze / thaw cycles.|
|Storage buffer||PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4|
|Background||Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.|
Western Blot analysis of various cells using CANX Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using CANX Polyclonal Antibody at dilution of 1:200.
Immunofluorescence analysis of Rat kidney tissue using CANX Polyclonal Antibody at dilution of 1:200.