CAV1 Polyclonal Antibody
- +1
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human;Mouse;Rat
- Applications: WB;IHC
Add to cart
For research use only. Order now, ship in 3 days
Product Details
Verified Samples |
Verified Samples in WB:Human fetal muscle,Human fetal lung,Human leiomyosarcoma,Mouse lung,Mouse heart,NIH/3T3 Verified Samples in IHC:Human esophagus cancer,Human cervical cancer |
Dilution |
WB 1:1000-1:5000, IHC 1:50-1:200 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human CAV1 |
Abbre | CAV1 |
Synonyms | BSCL3;CAV;CAV1;CAV1;caveolae protein;22 kD;caveolin 1 alpha isoform;caveolin 1 beta isoform;Caveolin 1 caveolae protein 22kDa;Caveolin-1;Caveolin1;cell growth-inhibiting protein 32;CGL3;LCCNS;MSTP085;OTTHUMP00000025031;PPH3;VIP 21;VIP21 |
Swissprot | |
Calculated MW | 20kDa |
Cellular Localization | Golgi apparatus membrane. Cell membrane. Membrane>caveola. Membrane raft. Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae. |
Concentration | 0.5 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Cardiovascular; Metabolism; Signal Transduction; Tags and Cell Markers |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol