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CAV1 Polyclonal Antibody

Cat:E-AB-13048
Manual MSDS
  • +1

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse;Rat
  • Applications: WB;IHC
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For research use only. Order now, ship in 3 days

Product Details
Verified Samples Verified Samples in WB:Human fetal muscle,Human fetal lung,Human leiomyosarcoma,Mouse lung,Mouse heart,NIH/3T3
Verified Samples in IHC:Human esophagus cancer,Human cervical cancer
Dilution

WB 1:1000-1:5000, IHC 1:50-1:200

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Synthetic peptide of human CAV1
Abbre CAV1
Synonyms BSCL3;CAV;CAV1;CAV1;caveolae protein;22 kD;caveolin 1 alpha isoform;caveolin 1 beta isoform;Caveolin 1 caveolae protein 22kDa;Caveolin-1;Caveolin1;cell growth-inhibiting protein 32;CGL3;LCCNS;MSTP085;OTTHUMP00000025031;PPH3;VIP 21;VIP21
Swissprot
Calculated MW 20kDa
Cellular Localization Golgi apparatus membrane. Cell membrane. Membrane>caveola. Membrane raft. Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae.
Concentration 0.5 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Cardiovascular; Metabolism; Signal Transduction; Tags and Cell Markers
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.