CBS Polyclonal Antibody

Uniprot : P35520
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14671

      Synonyms:AI047524,AI303044,Beta thionase,Beta-thionase,Cbs,Cbs cystathionine beta-synthase,CBS,Cystathionine beta synthase,Cystathionine beta-synthase,EC 4.2.1.22,HIP 4,HIP4,Methylcysteine synthase,MGC18856,MGC18895,MGC37300,OTTHUMP00000109416,OTTHUMP00000109418,Serine sulfhydrase

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms AI047524,AI303044,Beta thionase,Beta-thionase,Cbs,Cbs cystathionine beta-synthase,CBS,Cystathionine beta synthase,Cystathionine beta-synthase,EC 4.2.1.22,HIP 4,HIP4,Methylcysteine synthase,MGC18856,MGC18895,MGC37300,OTTHUMP00000109416,OTTHUMP00000109418,Serine sulfhydrase
      Swissprot P35520
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human CBS
      Application WB(Detection kit: E-IR-R304),ELISA
      Recommended dilution WB 1:200-1:1000
      Concentration 0.2 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm. Nucleus.
      Tissue specificity In the adult strongly expressed in liver and pancreas, some expression in heart and brain, weak expression in lung and kidney. In the fetus, expressed in brain, liver and kidney.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene.

      Images

      Western Blot analysis of Mouse pancreas and Human fetal liver tissue using CBS Polyclonal Antibody at dilution of 1:550

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