CBX3 Monoclonal Antibody

Uniprot : Q13185
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
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    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience

      Catalog number:E-AB-22270

      Synonyms:CBX 3,CBX3,CBX3,Chromobox homolog 3 (HP1 gamma homolog,Drosophila),Chromobox homolog 3,Chromobox protein homolog 3,GAMMA,HECH,Heterochromatin like protein 1,Heterochromatin protein 1 homolog gamma,Heterochromatin protein HP1 gamma,HP1 gamma,HP1 gamma homolog,HP1Hs gamma,Modifier 2 protein

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Mouse

      Reactivity: H,M,R

      Applications: WB,IHC-p

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms CBX 3,CBX3,CBX3,Chromobox homolog 3 (HP1 gamma homolog,Drosophila),Chromobox homolog 3,Chromobox protein homolog 3,GAMMA,HECH,Heterochromatin like protein 1,Heterochromatin protein 1 homolog gamma,Heterochromatin protein HP1 gamma,HP1 gamma,HP1 gamma homolog,HP1Hs gamma,Modifier 2 protein
      Swissprot Q13185
      Source Mouse
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant Protein of HP-1γ
      Application WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R217)
      Recommended dilution WB 1:500-2000, IHC 1:50-300
      Concentration 1 mg/mL
      Clonality Monoclonal

      Properties

      Cellular localization Nucleus. Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis.
      Clone No. Clone:4F4
      Isotype IgG
      Purification Protein A purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
      Background At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. 

      Images

      monoclonal antibody-Elabscience

      Western Blot analysis of 1) Hela, 2) 3T3, 3) PC12 cells using CBX3 Monoclonal Antibody at dilution of 1:1000.

      monoclonal antibody-Elabscience

      Immunohistochemistry of paraffin-embedded Human colon carcinoma tissue using CBX3 Monoclonal Antibody at dilution of 1:200.

      monoclonal antibody-Elabscience

      Immunohistochemistry of paraffin-embedded Human placenta tissue using CBX3 Monoclonal Antibody at dilution of 1:200.

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