CBX5 Monoclonal Antibody

Uniprot : P45973
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
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    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience

      Catalog number:E-AB-22146

      Synonyms:Antigen p25,CBX5,CBX5,CG8409,Chromobox 5,Chromobox homolog 5 (HP1 alpha homolog,Drosophila),Chromobox homolog 5,Chromobox protein homolog 5,Epididymis luminal protein 25,HEL25,Heterochromatin protein 1 alpha,Heterochromatin protein 1,Heterochromatin protein 1 homolog alpha,HP1 alpha,HP1 alpha homolog,HP1,HP1A,HP1Hs alpha,Su(var)205

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Mouse

      Reactivity: H,M,R

      Applications: WB,IHC-p

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Antigen p25,CBX5,CBX5,CG8409,Chromobox 5,Chromobox homolog 5 (HP1 alpha homolog,Drosophila),Chromobox homolog 5,Chromobox protein homolog 5,Epididymis luminal protein 25,HEL25,Heterochromatin protein 1 alpha,Heterochromatin protein 1,Heterochromatin protein 1 homolog alpha,HP1 alpha,HP1 alpha homolog,HP1,HP1A,HP1Hs alpha,Su(var)205
      Swissprot P45973
      Source Mouse
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant Protein of HP-1α
      Application WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R217)
      Recommended dilution WB 1:500-2000, IHC 1:50-300
      Concentration 1 mg/mL
      Clonality Monoclonal

      Properties

      Cellular localization Nucleus. Chromosome. Chromosome>centromere. Component of centromeric and pericentromeric heterochromatin. Associates with chromosomes during mitosis. Associates specifically with chromatin during metaphase and anaphase.
      Clone No. Clone:7B6
      Isotype IgG
      Purification Protein A purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
      Background This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

      Images

      monoclonal antibody-Elabscience

      Western Blot analysis of 1) Hela, 2)3T3, 3) PC-12 cells using CBX5 Monoclonal Antibody at dilution of 1:1000.

      monoclonal antibody-Elabscience

      Immunohistochemistry of paraffin-embedded Human uterus tissue using CBX5 Monoclonal Antibody at dilution of 1:200.

      monoclonal antibody-Elabscience

      Immunofluorescence analysis of Human uterus tissue using CBX5 Monoclonal Antibody at dilution of 1:200.

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