CD14 Polyclonal Antibody

Uniprot : P08571,P10810,Q63691
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      Catalog number:E-AB-70113

      Synonyms:CD 14,CD_antigen=CD14,CD14,CD14 antigen,CD14 molecule,CD14,LPS-R,Mo2,Monocyte differentiation antigen CD14,Monocyte differentiation antigen CD14 urinary form,Monocyte differentiation antigen CD14,membrane-bound form,Myeloid cell specific leucine rich glycoprotein,Myeloid cell-specific leucine-rich glycoprotein

      Size:
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $129

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms CD 14,CD_antigen=CD14,CD14,CD14 antigen,CD14 molecule,CD14,LPS-R,Mo2,Monocyte differentiation antigen CD14,Monocyte differentiation antigen CD14 urinary form,Monocyte differentiation antigen CD14,membrane-bound form,Myeloid cell specific leucine rich glycoprotein,Myeloid cell-specific leucine-rich glycoprotein
      Swissprot P08571,P10810,Q63691
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen KLH conjugated Synthetic peptide corresponding to Mouse CD14
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R217)
      Recommended dilution WB 1:500-1:2000, IHC 1:200-1:800
      Concentration 1 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm,Membrane
      Tissue specificity Detected on macrophages (at protein level) (PubMed:1698311). Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages. Highest expression level in liver.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
      Background CD14 is a 50-55 kDa glycosylphosphatidylinositol-anchored glycoprotein. CD14 is preferentially expressed on monocytes and macrophages. CD14 acts as a co-receptor (along with TLR4 and MD-2) for bacterial liposaccharides (LPS). It plays a major role in the inflammatory response of monocytes to LPS.

      Images

      Western Blot analysis of various samples using CD14 Polyclonal Antibody at dilution of 1:1000.

      Immunohistochemistry analysis of paraffin-embedded mouse lung using CD14 Polyclonal Antibody at dilution of 1:400.

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      MSDS for ELISA

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