CERS4 Polyclonal Antibody
- +1
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human
- Applications: WB;IHC
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Product Details
Verified Samples |
Verified Samples in WB:Human fetal liver,HT29,HUVEC,MCF-7,Human hepatocellsular carcinoma Verified Samples in IHC:Human ovarian cancer,Human prostate cancer |
Dilution |
WB 1:500-1:2000, IHC 1:50-1:200 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human CERS4 |
Abbre | CERS4 |
Synonyms | ceramide synthase 4;CerS4;FLJ12089;LAG1 homolog ceramide synthase 4;LAG1 longevity assurance homolog 4;LAG1;S. cerevisiae;homolog of;4;LASS 4;LASS4;LASS4 LAG1 homolog ceramide synthase 4;LASS4;TRAM homolog 1;Trh 1;Trh1 |
Swissprot | |
Calculated MW | 46kDa |
Cellular Localization | Nucleus membrane. Endoplasmic reticulum membrane. |
Concentration | 0.9 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Metabolism; Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol