CHD4 Polyclonal Antibody (E-AB-63554)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Rat liver, Human oophoroma, Mouse liver Verified Samples in IF: C6, L929, U-2OS |
| Dilution | IHC 1:100-1:200, IF 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, IF |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human CHD4 (NP_001264.2). |
| Abbre | CHD4 |
| Synonyms | CHD-4, CHD4, Mi-2b, Mi2-BETA, SIHIWES |
| Swissprot | |
| Cellular Localization | Nucleus. Cytoplasm>cytoskeleton>centrosome. Associates with centrosomes in interphase. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. |
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