CLDND1 Polyclonal Antibody (E-AB-14011)
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For research use only.
| Verified Samples | Verified Samples in IHC: Human colon cancer, Human brain |
| Dilution | IHC 1:50-1:200 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human CLDND1 |
| Abbre | CLDND1 |
| Synonyms | C3orf4, Chromosome 3 open reading frame 4, Claudin domain containing 1, Claudin domain containing 1 protein, GENX 3745, Membrane protein GENX3745, MGC111162, MGC3316, MGC9861, OTTHUMP00000, OTTHUMP00000217407, OTTHUMP00000217408, OTTHUMP00000217423, OTTHUMP00000217424, OTTHUMP00000217562, OTTHUMP00000217563, OTTHUMP00000217584, OTTHUMP00000217585, OTTHUMP00000217586, OTTHUMP00000217587, OTTHUMP00000217609, OTTHUMP00000217610, OTTHUMP00000217611, OTTHUMP00000217622, OTTHUMP00000217623, OTTHUMP00000217625, OTTHUMP00000217627, OTTHUMP00000217628, OTTHUMP00000217638抗体 |
| Swissprot | |
| Calculated MW | 28.6 kDa |
| Cellular Localization | Membrane, Multi pass membrane protein |
| Tissue Specificity | Widely distributed in the adult CNS with highest expression in the corpus callosum, caudate nucleus, cerebral cortex, medulla, putamen, spinal cord, substantia nigra and subthalamic nucleus. Weak expression was detected in the adult heart. |
| Concentration | 0.20 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell Biology, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20℃ Valid for 12 months. Avoid freeze/thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | CLDND1 (claudin domain containing 1), also known as C3orf4 or HSPC174, is a 253 amino acid multi-pass membrane protein that is expressed at high levels in adult brain and at lower levels in adult heart. Existing as two alternatively spliced isoforms, CLDND1 is encoded by a gene that maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. |
Product Recommendations for Literature Synchronization
Note: Data for this module come from published literature that cites this product, displaying other products used together in the same research paper.
| Cat.No. | Product Name | Sizes |
|---|---|---|
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 50mL , 18mL , 6mL , 3mL |
| E-IR-R220 | Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
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