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COL17A1 Polyclonal Antibody

Cat:E-AB-17809
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human; Mouse
  • Applications: IHC
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Product Details
Verified Samples Verified Samples in IHC:Human gastric cancer,Human breast cancer
Dilution

IHC 1:50-1:200

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Synthetic peptide of human COL17A1
Abbre COL17A1
Synonyms 180 kDa bullous pemphigoid antigen 2;Alpha 1 type XVII collagen;BA16H23.2;BP 180;BP180;BPA 2;BPAG 2;BPAG2;Bullous pemphigoid antigen 2;COL17A1;Collagen 17;Collagen alpha 1 XVII chain;Collagen alpha 1(XVII) chain;Collagen alpha1 XVII chain;Collagen type XVII alpha 1;Collagen XVII alpha 1 polypeptide;CollagenXVII;Epidermolysis bullosa junctional localisata variant;FLJ60881;KIAA0204;LAD 1;LAD1
Swissprot
Cellular Localization Cell junction, hemidesmosome. Membrane; Single-pass type II membrane protein. Note=Localized along the plasma membrane of the hemidesmosome. 120 kDa linear IgA disease antigen and 97 kDa linear IgA disease antigen: Secreted, extracellular space, extracellular matrix, basement membrane.
Concentration 0.6 mg/mL
Buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method Antigen affinity purification
Research Areas Cancer; Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Ice bag
background COL17A1 (Collagen Type XVII Alpha 1 Chain) is a Protein Coding gene. Diseases associated with COL17A1 include Epidermolysis Bullosa, Junctional, Non-Herlitz Type and Epithelial Recurrent Erosion Dystrophy. Among its related pathways are Collagen chain trimerization and Phospholipase-C Pathway. An important paralog of this gene is COL6A1.This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form.