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COL1A2 Polyclonal Antibody

Cat:E-AB-10155
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse;Rat
  • Applications: IHC
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Product Details
Verified Samples Verified Samples in IHC:Human colon cancer,Human lung cancer
Dilution

IHC 1:100-1:300

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Recombinant protein of human COL1A2
Abbre COL1A2
Synonyms Alpha 2 collagen type I;Alpha 2 type I collagen;Alpha 2 type I procollagen;Alpha 2(I) collagen;Alpha 2(I) procollagen;Alpha-2 type I collagen;CO1A2;COL1A2;Collagen alpha 2(I) chain;Collagen alpha-2(I) chain;Collagen I alpha 2 polypeptide;Collagen of skin tendon and bone alpha 2 chain;Collagen type I alpha 2;OI4;Osteogenesis imperfecta type IV;Type I procollagen
Swissprot
Cellular Localization Secreted>extracellular space>extracellular matrix.
Concentration 0.1 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Signal Transduction; Stem Cells
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.