COLEC12 Polyclonal Antibody

Uniprot : Q5KU26
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-17716

      Synonyms:CL P1,CL-P1,CLP1,COL12,COLEC 12,colec12,Collectin placenta 1,Collectin placenta protein 1,Collectin sub family member 12,Collectin-12,hCL P1,hCL-P1,NSR2,Nurse cell scavenger receptor 2,SCARA4,Scavenger receptor class A member 4,Scavenger receptor with C type lectin,Scavenger receptor with C-type lectin,SRCL

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms CL P1,CL-P1,CLP1,COL12,COLEC 12,colec12,Collectin placenta 1,Collectin placenta protein 1,Collectin sub family member 12,Collectin-12,hCL P1,hCL-P1,NSR2,Nurse cell scavenger receptor 2,SCARA4,Scavenger receptor class A member 4,Scavenger receptor with C type lectin,Scavenger receptor with C-type lectin,SRCL
      Swissprot Q5KU26
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthetic peptide of human COLEC12
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:30-150, ELISA 1:2000-10000
      Concentration 1.1 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Membrane. Forms clusters on the cell surface.
      Tissue specificity Expressed in perivascular macrophages. Expressed in plaques-surrounding reactive astrocytes and in perivascular astrocytes associated with cerebral amyloid angiopathy (CAA) in the temporal cortex of Alzheimer patient (at protein level). Strongly expressed in placenta. Moderately expressed in heart, skeletal muscle, small intestine and lung. Weakly expressed in brain, colon, thymus and kidney. Expressed in nurse-like cells. Expressed in reactive astrocytes and vascular/perivascular cells in the brain of Alzheimer patient.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells.

      Images

      Immunohistochemistry of paraffin-embedded Human brain tissue using COLEC12 Polyclonal Antibody at dilution 1:40

      Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using COLEC12 Polyclonal Antibody at dilution 1:40

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