COPS5 Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human;Mouse
- Applications: WB;IHC
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Product Details
Verified Samples |
Verified Samples in WB:Mouse liver Verified Samples in IHC:Human colon cancer |
Dilution |
WB 1:1000-1:5000, IHC 1:150-1:500 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human COPS5 |
Abbre | COPS5 |
Synonyms | 38 kDa Mov34 homolog;COP9 (constitutive photomorphogenic) homolog subunit 5;COP9 constitutive photomorphogenic homolog subunit 5;COP9 signalosome complex subunit 5;COP9 signalosome subunit 5;Cop9 subunit 5;COPS 5;cops5;CSN 5;CSN5;CSN5;JAB 1;Jun activation domain binding protein 1;Jun activation domain binding protein;Jun activation domain-binding protein 1;MGC3149;MOV 34;MOV34;MOV34 family;38-KD member;SGN 5;SGN5;Signalosome subunit 5 |
Swissprot | |
Calculated MW | 38kDa |
Cellular Localization | Cytoplasm. Nucleus. |
Concentration | 0.9 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Neuroscience; Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol