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COPS5 Polyclonal Antibody

Cat:E-AB-10415
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse
  • Applications: WB;IHC
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Product Details
Verified Samples Verified Samples in WB:Mouse liver
Verified Samples in IHC:Human colon cancer
Dilution

WB 1:1000-1:5000, IHC 1:150-1:500

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Recombinant protein of human COPS5
Abbre COPS5
Synonyms 38 kDa Mov34 homolog;COP9 (constitutive photomorphogenic) homolog subunit 5;COP9 constitutive photomorphogenic homolog subunit 5;COP9 signalosome complex subunit 5;COP9 signalosome subunit 5;Cop9 subunit 5;COPS 5;cops5;CSN 5;CSN5;CSN5;JAB 1;Jun activation domain binding protein 1;Jun activation domain binding protein;Jun activation domain-binding protein 1;MGC3149;MOV 34;MOV34;MOV34 family;38-KD member;SGN 5;SGN5;Signalosome subunit 5
Swissprot
Calculated MW 38kDa
Cellular Localization Cytoplasm. Nucleus.
Concentration 0.9 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Neuroscience; Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors