CORO1B Polyclonal Antibody (E-AB-19721)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer |
| Dilution | IHC 1:30-1:150 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CORO1B |
| Abbre | CORO1B |
| Synonyms | COR1B, CORO 1B, CORO1B, Coronin 1B, Coronin 2, Coronin actin binding protein 1B, Coronin-1B, Coronin-2, Coronin1B, Coronin2, DKFZP762I166, OTTHUMP00000236823 |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytoskeleton. Localized to the leading edge in fibroblasts, as well as weakly along actin stress fibers. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell motility (Cai et al., 2005 [PubMed 16027158]). Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction (By similarity). |
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