COX11 Polyclonal Antibody (E-AB-14015)
For research use only.
| Verified Samples |
Verified Samples in WB: Mouse brain Verified Samples in IHC: Human stomach cancer |
| Dilution | WB 1:1000-1:5000, IHC 1:25-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human COX11 |
| Abbre | COX11 |
| Synonyms | COX11P |
| Swissprot | |
| Calculated MW | 31 kDa |
| Cellular Localization | Mitochondrion, mitochondrial inner membrane, mitochondrion, Other locations: integral component of membrane, protein complex. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen.This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes.The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex.This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies.However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX.This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane.Multiple transcript variants encoding different isoforms have been found for this gene.A related pseudogene has been found on chromosome 6. |
Other Clones
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Other Formats
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Unconjugated
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