CTNNA1 Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human;Mouse
- Applications: WB;IHC
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Product Details
Verified Samples |
Verified Samples in WB:A431 Verified Samples in IHC:Human gastric cancer |
Dilution |
WB 1:500-1:2000, IHC 1:50-1:200 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human CTNNA1 |
Abbre | CTNNA1 |
Synonyms | Alpha E-catenin;Cadherin associated protein 102kDa;Cadherin associated protein;Cadherin-associated protein;CAP 102;CAP102;Catenin (cadherin associated protein) alpha 1 102kDa;Catenin (cadherin associated protein);alpha 1;102kDa;Catenin alpha 1;Catenin alpha-1;CTNA1;CTNNA 1;Ctnna1;FLJ36832;FLJ52416;MDPT2;NY REN 13 antigen;OTTHUMP00000224141;OTTHUMP00000224147;Renal carcinoma antigen NY REN 13;Renal carcinoma antigen NY-REN-13 |
Swissprot | |
Calculated MW | 100kDa |
Cellular Localization | Cell membrane and Cytoplasm>cytoskeleton. Cell junction>adherens junction. Cell membrane. Cell junction. Found at cell-cell boundaries and probably at cell-matrix boundaries. |
Concentration | 0.2 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Signal Transduction; Stem Cells |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | Catenin alpha-1is aproteinthat in humans is encoded by theCTNNA1gene. Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be mucHuman, Mouseore dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol