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CTNNA1 Polyclonal Antibody

Cat:E-AB-10207
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse
  • Applications: WB;IHC
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Product Details
Verified Samples Verified Samples in WB:A431
Verified Samples in IHC:Human gastric cancer
Dilution

WB 1:500-1:2000, IHC 1:50-1:200

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Recombinant protein of human CTNNA1
Abbre CTNNA1
Synonyms Alpha E-catenin;Cadherin associated protein 102kDa;Cadherin associated protein;Cadherin-associated protein;CAP 102;CAP102;Catenin (cadherin associated protein) alpha 1 102kDa;Catenin (cadherin associated protein);alpha 1;102kDa;Catenin alpha 1;Catenin alpha-1;CTNA1;CTNNA 1;Ctnna1;FLJ36832;FLJ52416;MDPT2;NY REN 13 antigen;OTTHUMP00000224141;OTTHUMP00000224147;Renal carcinoma antigen NY REN 13;Renal carcinoma antigen NY-REN-13
Swissprot
Calculated MW 100kDa
Cellular Localization Cell membrane and Cytoplasm>cytoskeleton. Cell junction>adherens junction. Cell membrane. Cell junction. Found at cell-cell boundaries and probably at cell-matrix boundaries.
Concentration 0.2 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Signal Transduction; Stem Cells
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background Catenin alpha-1is aproteinthat in humans is encoded by theCTNNA1gene. Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be mucHuman, Mouseore dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components.