CUL3 Polyclonal Antibody (E-AB-10263)
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For research use only.
| Verified Samples |
Verified Samples in WB: 293T Verified Samples in IHC: Human thyroid cancer, Human colon cancer |
| Dilution | WB 1:200-1:1000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human CUL3 |
| Abbre | CUL3 |
| Synonyms | CUL 3, CUL3, Cul-3, Cullin-3, Cullin3, KIAA0617, PHA2E, cul3 |
| Swissprot | |
| Calculated MW | 89 kDa |
| Cellular Localization | Nucleus. Golgi apparatus. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
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