DCK Polyclonal Antibody

Uniprot : P27707
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14732

      Synonyms:dCK,DCK protein,DCK,Deoxycytidine kinase,Deoxynucleoside kinase,EC 2.7.1,EC 2.7.1.74,MGC117410,MGC138632,OTTHUMP00000219118,OTTHUMP00000219119

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms dCK,DCK protein,DCK,Deoxycytidine kinase,Deoxynucleoside kinase,EC 2.7.1,EC 2.7.1.74,MGC117410,MGC138632,OTTHUMP00000219118,OTTHUMP00000219119
      Swissprot P27707
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human DCK
      Application WB(Detection kit: E-IR-R304),ELISA
      Recommended dilution WB 1:200-1:1000
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.

      Images

      Western Blot analysis of Mouse heart tissue using DCK Polyclonal Antibody at dilution of 1:550

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