DRAK2 Polyclonal Antibody

Uniprot : O94768
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14744

      Synonyms:DAP kinase related apoptosis inducing protein,DAP kinase related apoptosis inducing protein kinase 2,DAP kinase-related apoptosis-inducing protein kinase 2,Death associated protein kinase related 2,DRAK 2,DRAK2,Serine/threonine kinase 17b,Serine/threonine kinase 17b apoptosis inducing,Serine/threonine protein kinase 17B,Serine/threonine-protein kinase 17B,ST17B,STK 17B,Stk17b

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms DAP kinase related apoptosis inducing protein,DAP kinase related apoptosis inducing protein kinase 2,DAP kinase-related apoptosis-inducing protein kinase 2,Death associated protein kinase related 2,DRAK 2,DRAK2,Serine/threonine kinase 17b,Serine/threonine kinase 17b apoptosis inducing,Serine/threonine protein kinase 17B,Serine/threonine-protein kinase 17B,ST17B,STK 17B,Stk17b
      Swissprot O94768
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human STK17B
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.5 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus.
      Tissue specificity Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background The full-length STK17B cDNA clone encodes a deduced 372-amino acid protein with a molecular mass of 42.34 kD. The putative kinase domain is located at the N terminus and contains all 11 subdomains conserved among ser/thr kinases. STK17A and STK17B share 59.7% amino acid identity. Northern blot analysis revealed that STK17B was expressed in various tissues, such as heart, placenta, liver, and pancreas, as different-sized transcripts, presumably due to differences in the 3-prime untranslated region. Transient transfection of COS-7 cells showed that STK17B localized in nuclei. Phosphorylates myosin light chains. Acts as a positive regulator of apoptosis.

      Images

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using DRAK2 Polyclonal Antibody at dilution 1:40

      Immunohistochemistry of paraffin-embedded Human liver cancer tissue using DRAK2 Polyclonal Antibody at dilution 1:40

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