English Toll-free:1-888-852-8623 or Contact Us
Keyword cannot be empty !

DUSP12 Polyclonal Antibody

Cat:E-AB-10309
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse;Rat
  • Applications: WB
Add to cart

For research use only. Order now, ship in 3 days

Product Details
Verified Samples Verified Samples in WB:Jurkat
Dilution

WB 1:200-1:1000

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Recombinant protein of human DUSP12
Abbre DUSP12
Synonyms Dual specificity phosphatase 12;Dual specificity protein phosphatase 12;Dual specificity tyrosine phosphatase YVH1;DUS12;DUSP 1;DUSP 12;DUSP1;DUSP12;Serine/threonine specific protein phosphatase;TDSP4;YVH 1;YVH1;YVH1 protein tyrosine phosphatase (S. cerevisiae) ortholog;YVH1 protein tyrosine phosphatase ortholog
Swissprot
Calculated MW 38kDa
Cellular Localization Nucleus.
Concentration 0.4 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.