DUSP12 Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human;Mouse;Rat
- Applications: WB
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Product Details
Verified Samples |
Verified Samples in WB:Jurkat |
Dilution |
WB 1:200-1:1000 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human DUSP12 |
Abbre | DUSP12 |
Synonyms | Dual specificity phosphatase 12;Dual specificity protein phosphatase 12;Dual specificity tyrosine phosphatase YVH1;DUS12;DUSP 1;DUSP 12;DUSP1;DUSP12;Serine/threonine specific protein phosphatase;TDSP4;YVH 1;YVH1;YVH1 protein tyrosine phosphatase (S. cerevisiae) ortholog;YVH1 protein tyrosine phosphatase ortholog |
Swissprot | |
Calculated MW | 38kDa |
Cellular Localization | Nucleus. |
Concentration | 0.4 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol