DUSP12 Polyclonal Antibody

Uniprot : Q9UNI6
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14070

      Synonyms:Dual specificity phosphatase 12,Dual specificity protein phosphatase 12,Dual specificity tyrosine phosphatase YVH1,DUS12,DUSP 1,DUSP 12,DUSP1,DUSP12,Serine/threonine specific protein phosphatase,TDSP4,YVH 1,YVH1,YVH1 protein tyrosine phosphatase (S. cerevisiae) ortholog,YVH1 protein tyrosine phosphatase ortholog

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Dual specificity phosphatase 12,Dual specificity protein phosphatase 12,Dual specificity tyrosine phosphatase YVH1,DUS12,DUSP 1,DUSP 12,DUSP1,DUSP12,Serine/threonine specific protein phosphatase,TDSP4,YVH 1,YVH1,YVH1 protein tyrosine phosphatase (S. cerevisiae) ortholog,YVH1 protein tyrosine phosphatase ortholog
      Swissprot Q9UNI6
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human DUSP12
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.7 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus.
      Tissue specificity Ubiquitous, highest expression in spleen, testis, ovary, and peripheral blood leukocytes and lower expression in liver and lung.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.

      Images

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using DUSP12 Polyclonal Antibody at dilution 1:77

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