DUSP22 Polyclonal Antibody

Uniprot : Q9NRW4
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    <
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14065

      Synonyms:Dual specificity protein phosphatase 22,DUS22,Dusp22,JNK stimulatory phosphatase 1,JNK-stimulatory phosphatase-1,JSP 1,JSP-1,JSP1,LMW DSP2,LMW-DSP2,Low molecular weight dual specificity phosphatase 2,MAP kinase phosphatase x,Mitogen activated protein kinase phosphatase x,Mitogen-activated protein kinase phosphatase x,MKP-x,MKPX

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Dual specificity protein phosphatase 22,DUS22,Dusp22,JNK stimulatory phosphatase 1,JNK-stimulatory phosphatase-1,JSP 1,JSP-1,JSP1,LMW DSP2,LMW-DSP2,Low molecular weight dual specificity phosphatase 2,MAP kinase phosphatase x,Mitogen activated protein kinase phosphatase x,Mitogen-activated protein kinase phosphatase x,MKP-x,MKPX
      Swissprot Q9NRW4
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human DUSP22
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.4 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm. Nucleus.
      Tissue specificity Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.

      Images

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using DUSP22 Polyclonal Antibody at dilution 1:60

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