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For research use only.

Verified Samples Verified Samples in IF: A549
Dilution IF 1:50-1:100
Isotype IgG
Host Rabbit
Reactivity Human
Applications IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human DUSP22 (NP_064570.1).
Abbre DUSP22
Synonyms DUSP22,  JKAP,  JSP-1,  JSP1,  LMW-DSP2,  LMWDSP2,  MKP-x,  MKPX,  VHX
Swissprot
Cellular Localization Cytoplasm. Nucleus.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cell Biology,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.
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Unconjugated

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