ECT2 Polyclonal Antibody (E-AB-53424)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human gastric cancer |
| Dilution | IHC 1:50-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ECT2 |
| Abbre | ECT2 |
| Synonyms | ECT 2, ECT2 protein, Epithelial cell transforming sequence 2, Epithelial cell transforming sequence 2 oncogene, Epithelial cell transforming sequence 2 oncogene protein, FLJ10461, MGC138291 |
| Swissprot | |
| Cellular Localization | ECT2 exhibits nuclear localization in interphase, spreads throughout the cytoplasm in prometaphase, and is condensed in the midbody during cytokinesis. |
| Concentration | 1.02 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators.The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases.In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver.Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.Several transcript variants encoding different isoforms have been found for this gene. |
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