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For research use only.

Verified Samples Verified Samples in IHC: Human cervical cancer
Dilution IHC 1:30-1:150
Isotype Rabbit IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Full length fusion protein
Abbre ELMO1
Synonyms CED 12,  Ced 12 homolog,  Ced 12 homolog 1,  CED-12,  CED12,  Ced12 homolog,  Ced12 homolog 1,  ELMO 1,  ELMO-1,  ELMO1,  Engulfment and cell motility 1,  Engulfment and cell motility protein 1,  KIAA0281,  MGC126406,  Protein ced-12 homolog
Swissprot
Cellular Localization Cytoplasm. Cell membrane. Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.
Concentration 0.6 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Cancer,  Cell Biology,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the engulfment and cell motility protein family.These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration.Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy.Alternative splicing results in multiple transcript variants.
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