ELOVL1 Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human;Mouse
- Applications: IHC
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Product Details
Verified Samples |
Verified Samples in IHC:Human brain,Human liver cancer |
Dilution |
IHC 1:50-1:200 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human ELOVL1 |
Abbre | ELOVL1 |
Synonyms | 3 keto acyl CoA synthase ELOVL1;3-keto acyl-CoA synthase ELOVL1;CGI 88;Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 1;Elongation of very long chain fatty acids like 1;Elongation of very long chain fatty acids protein 1;ELOV1;ELOVL 1;ELOVL FA elongase 1;ELOVL fatty acid elongase 1;ELOVL1;Ssc1;Ssc1;mouse;homolog of;very long chain 3 oxoacyl CoA synthase 1;Very-long-chain 3-oxoacyl-CoA synthase 1 |
Swissprot | |
Cellular Localization | Endoplasmic reticulum,endoplasmic reticulum,endoplasmic reticulum membrane,integral component of endoplasmic reticulum membrane,Other locations:membrane |
Concentration | 0.6 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cardiovascular; Metabolism; Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | Elongation of very long chain fatty acid-like (ELOVL) proteins 1-6 are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids. The ELOVL proteins act as catalysts in fatty acid elongation reduction and localize to the endoplasmic reticulum (ER). Elongation of very long chain fatty acids protein 1 (ELOVL1), also referred to as Ssc1, is the human homolog of the yeast ELO3 protein. It is expressed in a variety of tissues and at especially high levels in stomach, skin, intestine, kidney and lung. ELOVL1 participates in the elongation of very long chain saturated and monounsaturated fatty acids of up to 26 carbons and may be required for the development of a barrier in epithelial cells and skin. ELOVL1 is also important for the formation of Myelin in the central nervous system. Impaired ELOVL1 activity may be associated with disorders of sphingolipid metabolism. |
Citations
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Gentiana lutea Extract Modulates Ceramide Synthesis in Primary and Psoriasis-Like Keratinocytes
IF:3.267
Journal:MOLECULES
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol