EPHB6 Polyclonal Antibody

Uniprot : O15197
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14687

      Synonyms:EPH receptor B6,Ephb6,EPHB6,Ephrin type B receptor 6 precursor,Ephrin type-B receptor 6,HEP,MGC129910,MGC129911,Tyrosine protein kinase defective receptor EPH 6,Tyrosine-protein kinase-defective receptor EPH-6

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms EPH receptor B6,Ephb6,EPHB6,Ephrin type B receptor 6 precursor,Ephrin type-B receptor 6,HEP,MGC129910,MGC129911,Tyrosine protein kinase defective receptor EPH 6,Tyrosine-protein kinase-defective receptor EPH-6
      Swissprot O15197
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human EPHB6
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.4 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Secreted and Membrane.
      Tissue specificity Expressed in brain. Expressed in non invasive breast carcinoma cell lines (at protein level). Strong expression in brain and pancreas, and weak expression in other tissues, such as heart, placenta, lung, liver, skeletal muscle and kidney. Expressed in breast non invasive tumors but not in metastatic lesions. Isoform 3 is expressed in cell lines of glioblastomas, anaplastic astrocytomas, gliosarcomas and astrocytomas. Isoform 3 is not detected in normal tissues.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants.

      Images

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using EPHB6 Polyclonal Antibody at dilution 1:40

      Immunohistochemistry of paraffin-embedded Human colon cancer tissue using EPHB6 Polyclonal Antibody at dilution 1:40

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