Factor IX Polyclonal Antibody

Uniprot : P00740
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14396

      Synonyms:Christmas Disease,Christmas factor,Coagulant factor IX,Coagulation factor 9,Coagulation factor IX,Coagulation factor IXa heavy chain,F9,FA9,Factor 9,Factor IX Deficiency,FactorIX,FIX,Haemophilia B,HEMB,MGC129641,MGC129642,P19,Plasma Thromboplastic Component,Plasma thromboplastin component,PTC

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Christmas Disease,Christmas factor,Coagulant factor IX,Coagulation factor 9,Coagulation factor IX,Coagulation factor IXa heavy chain,F9,FA9,Factor 9,Factor IX Deficiency,FactorIX,FIX,Haemophilia B,HEMB,MGC129641,MGC129642,P19,Plasma Thromboplastic Component,Plasma thromboplastin component,PTC
      Swissprot P00740
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human F9
      Application WB(Detection kit: E-IR-R304),ELISA
      Recommended dilution WB 1:500-1:2000
      Concentration 0.2 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Secreted.
      Tissue specificity Synthesized primarily in the liver and secreted in plasma.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.

      Images

      Western Blot analysis of Human liver cancer tissue, hela and Jurkat cell using Factor IX Polyclonal Antibody at dilution of 1:400

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