FBXO31 Polyclonal Antibody (E-AB-16428)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human gastric cancer, Human brain |
| Dilution | IHC 1:50-1:200 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human FBXO31 |
| Abbre | FBXO31 |
| Synonyms | DKFZp434B027, DKFZp434J1815, F box only protein 31, F box protein 31, F-box only protein 31, FBX14, FBX31, FBXO14, Fbxo31, FLJ22477, MGC15419, MGC9527, pp2386, Putative breast cancer tumor suppressor, SCF ubiquitin ligase specificity factor, SCF ubiquitin ligase specificity factor抗体 |
| Swissprot | |
| Cellular Localization | Cytoskeleton, centrosome, Cytosol, Other locations: neuronal cell body, SCF ubiquitin ligase complex. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants. |
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