FITC Anti-Human CD28 Antibody[CD28.2] (E-AB-F1195C)

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Cell Markers

Size	Price	Qty
100Tests	$ 78.00	- +
20Tests	$ 25.00	- +
100Tests×2	$ 132.00	- +

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Conjugation: FITC

Isotype	Mouse IgG1, κ
Host	Mouse
Reactivity	Human
Applications	FCM
Clonality	Monoclonal
Isotype Control	FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Abbre	CD28
Synonyms	GPSAT, GYPA, HGpMiX, MNS, PAS2
Swissprot	P10747
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Costimulatory Molecules, Immunology
Clone No.	CD28.2
Conjugation	FITC
Conjugation Information	FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.