Alternate Names	ADP-ribosyl cyclase 1,ADPRC 1,CD38,NIM-R5 antigen,2'-phospho-cyclic-ADP-ribose transferase
Swissprot	P56528
References	1. Oliver AM, et al. 1997. J. Immunol. 158:1108. 2. Howard M, et al. 1993. Science 262:1056.

Product Details

Form	Liquid
Clone No.	NIMR5(See Other Available Formats)
Host	Rat
Isotype	Rat IgG2a, κ
Isotype Control	FITC Rat IgG2a, κ Isotype Control[2A3] [Product E-AB-F09833C]
Reactivity	Mouse
Application	FCM (See the Application Description)
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Recommended Use	Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10⁶ cells in 100 μL volume].
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	FITC
	FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).

How to select the appropriate detection channel through the spectrogram?

Background

CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, a subset of T cells, brain, muscle, and kidney. In mouse, CD38 expression is downregulated on germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and metabolism of cADPR and NAADP. CD31 is the ligand of CD38.

Protocols & Troubleshootings

Related Protocols	Staining Cell Surface Targets for Flow Cytometry
Troubleshooting	Troubleshooting for Flow Cytometry

Alternative Formats

Product Name	Sizes	Price
AF/LE Purified Anti-Mouse CD38 Antibody[NIMR5]	50μg, 500μg, 1mg	Check More
Purified Anti-Mouse CD38 Antibody[NIMR5]	25μg, 100μg	Check More
FITC Anti-Mouse CD38 Antibody[NIMR5]	50Tests, 100Tests, 100Tests×2	Check More
PE Anti-Mouse CD38 Antibody[NIMR5]	50Tests, 100Tests, 100Tests×2	Check More
APC Anti-Mouse CD38 Antibody[NIMR5]	50Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine7 Anti-Mouse CD38 Antibody[NIMR5]	50Tests, 100Tests, 100Tests×2	Check More
PE Anti-Mouse CD38 Antibody[NIMR5]	25μg, 100μg	Check More
APC Anti-Mouse CD38 Antibody[NIMR5]	25μg, 100μg	Check More
PE/Cyanine7 Anti-Mouse CD38 Antibody[NIMR5]	25μg, 100μg	Check More

Citations

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