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FITC Anti-Mouse/Human CD11b Antibody[M1/70]

  • Cat.No.:E-AB-F1081UC

  • Applications: FCM
  • Isotype: Rat IgG2b, κ
  • Host: Rat

To Purchase E-AB-F1081UC

Size:
  • 25μg
  • 100μg
Price: $25
Qty:

Antigen Details

Alternate Names Integrin alpha-M,Itgam,CD11 antigen-like family member B,CR-3 alpha chain,Leukocyte adhesion receptor MO1,CD11b
Swissprot P05555,P11215
References
1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Product Details

Form Liquid
Clone No. M1/70
Host Rat
Isotype Rat IgG2b, κ
Isotype Control FITC Rat IgG2b, κ Isotype Control[LTF-2] [Product E-AB-F09843C]
Reactivity Human,Mouse
Application FCM
Storage Buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Recommended Use Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Shipping Biological ice pack at 4℃
Stability & Storage Keep as concentrated solution.
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
Conjugation FITC
FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).


How to select the appropriate detection channel through the spectrogram?

Background

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Protocols & Troubleshootings

Related Protocols Staining Cell Surface Targets for Flow Cytometry
Troubleshooting

Troubleshooting for Flow Cytometry

Alternative Formats

Product Name Sizes Price
AF/LE Purified Anti-Mouse/Human CD11b Antibody[M1/70] 50μg, 500μg, 1mg Check More
Purified Anti-Mouse/Human CD11b Antibody[M1/70] 25μg, 100μg Check More
Biotin Anti-Mouse/Human CD11b Antibody[M1/70] 25μg, 100μg Check More
FITC Anti-Mouse/Human CD11b Antibody[M1/70] 50Tests, 100Tests, 100Tests×2 Check More
PE Anti-Mouse/Human CD11b Antibody[M1/70] 50Tests, 100Tests, 100Tests×2 Check More
APC Anti-Mouse/Human CD11b Antibody[M1/70] 50Tests, 100Tests, 100Tests×2 Check More
PerCP Anti-Mouse/Human CD11b Antibody[M1/70] 50Tests, 100Tests, 100Tests×2 Check More
PE/Cyanine5 Anti-Mouse/Human CD11b Antibody[M1/70] 50Tests, 100Tests, 100Tests×2 Check More
PE/Cyanine7 Anti-Mouse/Human CD11b Antibody[M1/70] 50Tests, 100Tests, 100Tests×2 Check More
PE/Cyanine5.5 Anti-Mouse/Human CD11b Antibody[M1/70] 50Tests, 100Tests, 100Tests×2 Check More
PerCP/Cyanine5.5 Anti-Mouse/Human CD11b Antibody[M1/70] 50Tests, 100Tests, 100Tests×2 Check More
Elab Fluor® 488 Anti-Mouse/Human CD11b Antibody[M1/70] 50Tests, 100Tests, 100Tests×2 Check More
Elab Fluor® 647 Anti-Mouse/Human CD11b Antibody[M1/70] 50Tests, 100Tests, 100Tests×2 Check More
PE/Elab Fluor® 594 Anti-Mouse/Human CD11b Antibody[M1/70] 50Tests, 100Tests, 100Tests×2 Check More
Elab Fluor® Violet 450 Anti-Mouse/Human CD11b Antibody[M1/70] 50Tests, 100Tests, 100Tests×2 Check More
Elab Fluor® Red 780 Anti-Mouse/Human CD11b Antibody[M1/70] 50Tests, 100Tests, 100Tests×2 Check More
PE Anti-Mouse/Human CD11b Antibody[M1/70] 25μg, 100μg Check More
APC Anti-Mouse/Human CD11b Antibody[M1/70] 25μg, 100μg Check More
PerCP Anti-Mouse/Human CD11b Antibody[M1/70] 25μg, 100μg Check More
PE/Cyanine5 Anti-Mouse/Human CD11b Antibody[M1/70] 25μg, 100μg Check More
PE/Cyanine7 Anti-Mouse/Human CD11b Antibody[M1/70] 25μg, 100μg Check More
PE/Cyanine5.5 Anti-Mouse/Human CD11b Antibody[M1/70] 25μg, 100μg Check More
PerCP/Cyanine5.5 Anti-Mouse/Human CD11b Antibody[M1/70] 25μg, 100μg Check More
Elab Fluor® 488 Anti-Mouse/Human CD11b Antibody[M1/70] 25μg, 100μg Check More
Elab Fluor® 647 Anti-Mouse/Human CD11b Antibody[M1/70] 25μg, 100μg Check More
PE/Elab Fluor® 594 Anti-Mouse/Human CD11b Antibody[M1/70] 25μg, 100μg Check More
Elab Fluor® Violet 450 Anti-Mouse/Human CD11b Antibody[M1/70] 25μg, 100μg Check More
Elab Fluor® Red 780 Anti-Mouse/Human CD11b Antibody[M1/70] 25μg, 100μg Check More

Citations

  1. EUROPEAN JOURNAL OF PHARMACOLOGY (2022) IF: 5.195
    Geniposide inhibits SphK1 membrane targeting to restore macrophage polarization balance in collagen-induced arthritis mice

    DOI: 10.1016/j.ejphar.2022.175271

    PMID: 36108735

    Sample: Bmdms,Raw264.7 Cell
  2. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022) IF: 6.208
    Hepatocyte-Derived Prostaglandin E2-Modulated Macrophage M1-Type Polarization via mTOR-NPC1 Axis-Regulated Cholesterol Transport from Lysosomes to the Endoplasmic Reticulum in Hepatitis B Virus x Protein-Related Nonalcoholic Steatohepatitis

    DOI: 10.3390/ijms231911660

    PMID: 36232960

    Sample: Kupffer Cells
  3. PeerJ (2022) IF: 2.984
    3,4-dihydroxyphenylethyl alcohol glycoside reduces acetaminophen-induced acute liver failure in mice by inhibiting hepatocyte ferroptosis and pyroptosis

    DOI: 10.7717/peerj.13082

    PMID: 35310165

    Sample: Liver Tissue
  4. Pharmaceutics (2021) IF: 6.321
    A Melanin-like Nanoenzyme for Acute Lung Injury Therapy via Suppressing Oxidative and Endoplasmic Reticulum Stress Response

    DOI: 10.3390/pharmaceutics13111850

    PMID: 34834263

    Sample: Bronchoalveolar Lavage Fluid
  5. Oxidative Medicine and Cellular Longevity (2023) IF: 7.31
    Combination Therapy with Indigo and Indirubin for Ulcerative Colitis via Reinforcing Intestinal Barrier Function

    DOI: 10.1155/2023/2894695

    Sample: Colonic Lamina Propria Cell
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