FITC Anti-Mouse Ly6A/E(Sca-1) Antibody[D7] (E-AB-F1191C)

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Cell Markers

Size	Price	Qty
100Tests	$ 60.00	- +
50Tests	$ 42.00	- +
100Tests×2	$ 90.00	- +

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Conjugation: FITC

Isotype	Rat IgG2a, κ
Host	Rat
Reactivity	Mouse
Applications	FCM
Clonality	Monoclonal
Isotype Control	FITC Rat IgG2a, κ Isotype Control[2A3]
Abbre	Ly6A/E
Synonyms	Ly-6A.2/Ly-6E.1, Ly6, Ly6a, SCA-1, TAP
Swissprot	P05533
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Immunology, Stem Cells
Clone No.	D7
Conjugation	FITC
Conjugation Information	FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.