GPSM2 Polyclonal Antibody (E-AB-19960)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human tonsil |
| Dilution | IHC 1:30-1:150 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human GPSM2 |
| Abbre | GPSM2 |
| Synonyms | DFNB82, G protein signalling modulator 2, G protein signalling modulator 2 (AGS3 like C. elegans), G-protein-signaling modulator 2, GPSM2, Gpsm2, HGNC:29501, LGN, LGN protein, Mosaic protein LGN, Pins |
| Swissprot | |
| Cellular Localization | Cytoplasm. Cytoplasm>cell cortex. Localizes in the cytoplasm in the interphase and at cell periphery in the metaphase. |
| Concentration | 1.92 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cell Biology, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses.The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange.This protein may play a role in neuroblast division and in the development of normal hearing.Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82).Alternative splicing results in multiple transcript variants. |
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