GRIN1 Polyclonal Antibody (E-AB-12599)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human esophagus cancer, Human liver cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human GRIN1 |
| Abbre | GRIN1 |
| Synonyms | GluN1, Glutamate [NMDA] receptor subunit zeta-1, Glutamate receptor ionotropic, Glutamate receptor ionotropic N methyl D aspartate 1, Grin1, MRD8, N methyl D aspar, N methyl D aspartate receptor, N-methyl-D aspartate, NMDA 1, glutamate receptor ionotropic, subunit 1 |
| Swissprot | |
| Cellular Localization | Cell membrane. Cell junction>synapse>postsynaptic cell membrane. Cell junction>synapse>postsynaptic cell membrane>postsynaptic density. Enriched in post-synaptic plasma membrane and post-synaptic densities. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. |
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