GRM3 Polyclonal Antibody

Uniprot : Q14832
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    <
    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14110

      Synonyms:GLUR3,Glutamate metabotropic receptor 3,Glutamate receptor metabotropic 3,GPRC1C,GRM3,GRM3,Metabotropic glutamate receptor 3,MGlu3,mGluR3

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms GLUR3,Glutamate metabotropic receptor 3,Glutamate receptor metabotropic 3,GPRC1C,GRM3,GRM3,Metabotropic glutamate receptor 3,MGlu3,mGluR3
      Swissprot Q14832
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human GRM3
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.2 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell membrane.
      Tissue specificity Detected in brain cortex, thalamus, subthalamic nucleus, substantia nigra, hypothalamus, hippocampus, corpus callosum, caudate nucleus and amygdala.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. 

      Images

      Immunohistochemistry of paraffin-embedded Human brain tissue using GRM3 Polyclonal Antibody at dilution 1:50

      Immunohistochemistry of paraffin-embedded Human liver cancer tissue using GRM3 Polyclonal Antibody at dilution 1:50

      • Show all (0)
      • Reviews (0)
      • Q&A (0)
      ... Show All Show Less
      MSDS for ELISA

      Browsing History


        People Also Bought