HCK Polyclonal Antibody

Uniprot : P08631
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    <
    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14119

      Synonyms:Bmk,Hck 1,Hck,HCK,Hemopoietic cell kinase,JTK9,p59-HCK/p60-HCK,p59Hck,p59HCK/p60HCK,p61Hck,Tyrosine protein kinase HCK,Tyrosine-protein kinase HCK

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Bmk,Hck 1,Hck,HCK,Hemopoietic cell kinase,JTK9,p59-HCK/p60-HCK,p59Hck,p59HCK/p60HCK,p61Hck,Tyrosine protein kinase HCK,Tyrosine-protein kinase HCK
      Swissprot P08631
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human HCK
      Application WB(Detection kit: E-IR-R304),ELISA
      Recommended dilution WB 1:200-1:1000
      Concentration 0.2 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Membrane. Cytoplasm. At least half of this isoform is found in the cytoplasm, some of this fraction is myristoylated and Membrane. Membrane>caveola. 20% of this isoform is associated with caveolae, this association depends on palmitoylation of cyteine at position 3.
      Tissue specificity Expressed predominantly in cells of the myeloid and B-lymphoid lineages.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon. 

      Images

      Western Blot analysis of Hela cell using HCK Polyclonal Antibody at dilution of 1:500

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