HK1 Polyclonal Antibody

Uniprot : P19367
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14707

      Synonyms:BB404130,Brain form hexokinase,dea,DrHXK1,EC 2.7.1.1,Glycolytic enzyme,HEXOKIN,hexokinase I,Hexokinase PI,Hexokinase type I,Hexokinase,tumor isozyme,Hexokinase-1,Hexokinase-A,HK I,HK1,HK1 tb,Hk1-s,HK1-ta,HK1-tb,HK1-tc,HKD,HKI,HMSNR,HXK1,HXK1,im:7148527,mHk1-s,wu:fc09d08,wu:fc16e02,wu:fc21e02,wu:fq14b11,zgc:55790,zgc:77618

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms BB404130,Brain form hexokinase,dea,DrHXK1,EC 2.7.1.1,Glycolytic enzyme,HEXOKIN,hexokinase I,Hexokinase PI,Hexokinase type I,Hexokinase,tumor isozyme,Hexokinase-1,Hexokinase-A,HK I,HK1,HK1 tb,Hk1-s,HK1-ta,HK1-tb,HK1-tc,HKD,HKI,HMSNR,HXK1,HXK1,im:7148527,mHk1-s,wu:fc09d08,wu:fc16e02,wu:fc21e02,wu:fq14b11,zgc:55790,zgc:77618
      Swissprot P19367
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human HK1
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.5 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Mitochondrion outer membrane. Its hydrophobic N-terminal sequence may be involved in membrane binding.
      Tissue specificity Isoform 2 is erythrocyte specific. Isoform 3 and isoform 4 are testis-specific.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms.

      Images

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using HK1 Polyclonal Antibody at dilution 1:50

      Immunohistochemistry of paraffin-embedded Human colon cancer tissue using HK1 Polyclonal Antibody at dilution 1:50

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