HLA-G Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human
- Applications: IHC
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Product Details
Verified Samples |
Verified Samples in IHC:Human esophagus cancer |
Dilution |
IHC 1:50-1:300 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human HLA-G |
Abbre | HLA-G |
Synonyms | B2 microglobulin;DADB-15K14.8;HLA 6.0;HLA class I histocompatibility antigen alpha chain G;HLA class I histocompatibility antigen;alpha chain G;HLA class I molecule;HLA G;HLA G antigen;HLA G histocompatibility antigen class I G;HLA G3;HLA-G;HLA-G histocompatibility antigen;class I;HLA60;HLAG;HLAG;Major histocompatibility complex class I G;MHC class I antigen;MHC class I antigen G;MHC G;T-cell A locus;TCA |
Swissprot | |
Cellular Localization | Membrane. |
Concentration | 1.26 mg/mL |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cancer; Immunology |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Ice bag |
background | Human major histocompatibility complex (MHC) antigens,also referred to as human leukocyte antigens (HLA),are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface,where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance. |
Citations
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Functional HLA-C expressing trophoblast spheroids as a model to study placental–maternal immune interactions during human implantation
IF:4.38
Journal:Scientific Reports
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol