Human CA9 Antibody Pair Set (E-KAB-0415)
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For research use only.
| Background |
Carbonic anhydrases ( CAs ) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes , including respiration , calcification , acid-base balance , bone resorption , and the formation of aqueous humor , cerebrospinal fluid , saliva , and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma , but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation.
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| Synonyms |
CAIX, CA-IX, MN, Carbonic Dehydratase, RCC-Associated Protein G250
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| Swissprot | |
| Reactivity |
Human
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| Specificity |
Detects Human CA9 in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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