Human FOLR1 Antibody Pair Set (E-KAB-0427)
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For research use only.
| Background |
Folate receptor 1 ( FOLR1 ) ;also known as folate receptor alpha or adult folate-binding protein ( FBP ) ;is a 38-kDa glycoprotein belonging to the folate receptor family . The receptor binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. FOLR1 is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. FOLR1 expression is often limited to the apical surfaces of epithelium in the lung;kidney and choroid plexus but is differentially overexpressed in a variety of solid tumors such as ovarian cancer;non-small cell lung cancer;breast cancer;kidney cancer and high-grade osteosarcoma .
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| Synonyms |
FBP, FOLR, FR-alpha, Folate receptor alpha, MOv18, Adult folate-binding protein, KB cells FBP, Ovarian tumor-associated antigen MOv18
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| Swissprot | |
| Reactivity |
Human
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| Specificity |
Detects Human FOLR1 in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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