Human FSTL3 Antibody Pair Set (E-KAB-0426)
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For research use only.
| Background |
Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family , such as activin , BMP2 and MSTN. Inhibits activin A- , activin B- , BMP2- and MSDT-induced cellular signaling , more effective on activin A than on activin B. Involved in bone formation , inhibits osteoclast differentiation. Involved in hematopoiesis , involved in differentiation of hemopoietic progenitor cells , increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 or the nuclear form is probably involved in transcriptional regulation via interaction with MLLT10.
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| Synonyms |
FSTL3, FSRP, Follistatin-Related Protein, Follistatin Like 3, Follistatin-Like 3 ( Secreted Glycoprotein ), Follistatin-Related Protein 3
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| Swissprot | |
| Reactivity |
Human
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| Specificity |
Detects Human FSTL3 in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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